SS-31 10mg
SS-31 (Elamipretide) is a small, aromatic peptide that easily penetrates cell and organelle membranes. It is known to interfere with the production of reactive oxygen species (ROS or free radicals) and promote energy production in cells by stabilizing the enzyme cardiolipin within mitochondria. Cardiolipin is a crucial component of the inner mitochondrial membrane, fundamental to the electron transport chain, the machinery by which most cellular energy is produced.
SS-31 (Elamipretide) is a small, aromatic peptide that easily penetrates cell and organelle membranes. It is known to interfere with the production of reactive oxygen species (ROS or free radicals) and promote energy production in cells by stabilizing the enzyme cardiolipin within mitochondria. Cardiolipin is a crucial component of the inner mitochondrial membrane, fundamental to the electron transport chain, the machinery by which most cellular energy is produced.
SS-31 (Elamipretide) is a small, aromatic peptide that easily penetrates cell and organelle membranes. It is known to interfere with the production of reactive oxygen species (ROS or free radicals) and promote energy production in cells by stabilizing the enzyme cardiolipin within mitochondria. Cardiolipin is a crucial component of the inner mitochondrial membrane, fundamental to the electron transport chain, the machinery by which most cellular energy is produced.
Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabled as a drug, food or cosmetic.
What is SS-31?
SS-31 is a peptide that targets mitochondria, the powerhouses of cells, to improve their function and enhance the production of energy via ATP synthesis. It stabilizes cardiolipin, an essential component of the mitochondrial inner membrane, supporting the electron transport chain's efficiency and reducing the production of reactive oxygen species. This action helps mitigate oxidative stress and inflammation, which are implicated in various chronic diseases.
Key Functions and Benefits
Mitochondrial Function: Improves mitochondrial function, enhancing cellular energy production through ATP synthesis.
Inflammation Reduction: Reduces inflammatory cytokines, helping to mitigate oxidative stress and inflammation.
Disease Mitigation: Offers potential benefits for conditions such as Alzheimer’s, Parkinson’s, heart disease, diabetes, and kidney disease by improving mitochondrial health.
Mechanisms of Action
SS-31’s primary mechanisms of action include:
Cardiolipin Stabilization: Stabilizes cardiolipin, a key component of the inner mitochondrial membrane, essential for the electron transport chain's function.
Reactive Oxygen Species Reduction: Interferes with the production of reactive oxygen species, reducing oxidative stress.
Energy Production Enhancement: Promotes energy production in cells by enhancing ATP synthesis, supporting overall cellular function.
Unique Characteristics
SS-31’s ability to penetrate cell and organelle membranes, stabilize cardiolipin, and reduce reactive oxygen species makes it unique among peptides. It has shown promise in clinical trials as a potential treatment for mitochondrial myopathy, a group of neuromuscular disorders caused by mitochondrial damage, characterized by muscle weakness, exercise intolerance, heart failure, seizures, and dementia.
SS-31 Peptide Structure
Sequence: H-D-Arg-Tyr(2,6-diMe)-Lys-Phe-NH2
Molecular Formula: C32H49N9O5
Molecular Weight: 639.8 g/mol
PubChem CID: 11764719
CAS Number: 736992-21-5
Synonyms: Elamipretide, MTP-131, Bendavia
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat, or cure any medical condition, ailment, or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.